An Advanced Biochemistry Blog

Wilson Disease: An Inborn Error of Copper Metabolism

Wilson Disease, also known as Wilson’s Disease or hepatolenticular degeneration, was first described in 1912 by Samuel Wilson. Wilson found that his patients had many psychiatric symptoms, and often could not control their movements or facial expressions. Patients were also noted to have severe liver damage at the time of …

Reflection Blog #3

Wilson’s Disease (WD) is an inborn error of copper metabolism characterized by a toxic accumulation of copper in the liver and brain. In my research of WD, I have found salient themes that I think represent the progress in understanding the disease from when it was first described in 1912 …

A New Approach to Treating Viral Infections: Modified Carbohydrates Exhibiting Virucidal Activity

Original Paper: Jones ST, Cagno V, Janeček M, et al. Modified cyclodextrins as broad-spectrum antivirals. Sci Adv. 2020;6(5):eaax9318. doi:10.1126/sciadv.aax9318 – https://advances.sciencemag.org/content/6/5/eaax9318 Viral infections are very difficult to treat and cause some of the deadliest diseases in the world. For example, AIDS, which is caused by HIV (human immunodeficiency virus), remains …

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